1. (noun)keynote the principal theme in a speech or literary work Synonyms: tonic
2. (noun)keynote a fundamental or central idea Synonyms: tonic
3. (verb)tonic, keynote (music) the first note of a diatonic scale Synonyms: soda water, tonic water, tonic, soda pop, quinine water, keynote, soda, restorative, pop
4. (verb)keynote set the keynote of
5. (verb)keynote give the keynote address to (an audience)