1. (adj)thickened made or having become thick Synonyms: callous, calloused Antonyms: thin, tender, untoughened
2. (adj)calloused, callous, thickened having calluses; having skin made tough and thick through wear Synonyms: calloused, callous, indurate, pachydermatous, thickened Antonyms: thin, untoughened, tender
3. (adj)thickened made thick in consistency Synonyms: callous, calloused Antonyms: tender, thin, untoughened