1. (adj) annoying, bothersome, galling, irritating, nettlesome, pesky, pestering, pestiferous, plaguy, plaguey, teasing, vexatious, vexing
causing irritation or annoyance
Synonyms: irritating, exasperating, corruptive, pestilential, petulant, bothersome, mocking, galling, pestilent, cranky, perversive, pesky, scratchy, pestiferous, pettish, nettlesome, dirty, vexing, painful, irritable, plaguey, quizzical, peevish, irritative, plaguy, maddening, infuriating, annoying, tetchy, testy, fractious, techy, vexatious, pestering, peckish, teasing
Antonyms: good-natured, agreeable
2. (adj) cranky, fractious, irritable, nettlesome, peevish, peckish, pettish, petulant, scratchy, testy, tetchy, techy
easily irritated or annoyed
Synonyms: irritating, rough, tender, bothersome, galling, cranky, gravelly, crank, pesky, scratchy, pettish, pestiferous, pestering, abrasive, uneven, vexing, petulant, irritable, excitable, plaguey, refractory, teasing, tippy, peevish, rasping, recalcitrant, nettlesome, fractious, plaguy, tetchy, testy, spotty, techy, vexatious, raspy, peckish, annoying, grating
Antonyms: agreeable, good-natured
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Synonyms and Antonyms of nettlesome 
