1. paroxysm Pain is the most general term of this group, including all the others; pain is a disturbing sensation from which nature revolts, resulting from some injurious external interference (as from a wou Synonyms: pain, ache, distress, suffering, torture, agony, pang, throe, twinge, anguish, paroxysm, torment, wo(e) Antonyms: comfort, delight, ease, enjoyment, peace, rapture, relief, solace