1. (noun) substitution, permutation, transposition, replacement, switch
an event in which one thing is substituted for another
Synonyms: reversal, refilling, replacing, exchange, commutation, renewal, switch, substitution, replenishment, surrogate, heterotaxy, successor, switching, shift, replacement, alternate, permutation, electrical switch, transposition, substitute, electric switch
2. (noun) substitution, exchange, commutation
the act of putting one thing or person in the place of another: "he sent Smith in for Jones but the substitution came too late to help"
Synonyms: switch, rally, substitution, commutation, exchange, replacement, telephone exchange, transposition, commuting, central, re-sentencing, permutation, interchange
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Synonyms for substitution 
